When a 9-year-old girl vanishes on her way to school, the entire community helps with the search; detectives believe her mother may be involved, and a hidden fingerprint seals the case.

The investigation of a murder case in New Jersey is stalled until a similar attack occurs on a state trooper in Maine.

A young woman goes missing without leaving many clues, but the advanced technology on offer makes it possible for cat hairs and insects to help build an image of the abductor.

Blood spatter analysis and an investigation lead police to the truth when a pregnant woman is found dead in her home.

A mother is determined to discover what happened when her daughter is injured in a hit-and-run accident.

Forensic science and deductive reasoning determine what happened to a mother and daughter while they were on a shopping spree.

Exploring how an American hit single from 1966 - "The Cheater" by Bob Kuban and the In-Men - foreshadowed the demise of the group's lead singer, Walter Scott.

Eight years after a man confessed to the murder of a young woman, another man claims that he committed the crime, and investigators must use forensic evidence to determine the true killer.

Although a group of teenage thugs are suspected of attacking two boys on a fishing trip, there is no solid evidence until a murky fishing hole provides some answers.

When young prostitute's body turns up in an Ohio waterway, authorities have one tiny clue which could point to her killer, but face huge challenges due to her policemen clients and DNA evidence being washed away.

In a small South Carolina town in 1991, 17-year-old Crystal Faye Todd, a popular high school student, is raped, murdered and dumped in a deserted field; with few leads, authorities test the DNA of several friends, and one match shocks everyone.

In a groundbreaking case using animal DNA, investigators use forensic testing on a cat to help them solve the case of a woman who vanished from her home on Prince Edward Island.

A look into the 1984 Oregon food poisonings, where detectives track down the outbreak to a cult which aims to use germ warfare to take down the government.

A woman is found dead from a gunshot wound and police suspect her husband, however, forensic teams prove what really happened and the truth is stranger than fiction.

A Texas love triangle turns deadly, and it appears to be an open-and-shut case until technology tells the tale.

After the discovery of the brutal murder of an 18-year-old desk clerk of a beachfront condo, analysts use brand-new mitochondrial DNA technology to prove the killer's identity.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Ted Kacyznski's brother, the man who ultimately turned him in to the authorities, discusses the hunt that led to the capture of the Unabomber.

Bizarre drawings and puzzling clues found in Heath Ledger's apartment could possibly give clues as to whether or not his portrayal as The Joker impacted his life.

DC Madam,Deborah Jean Palfrey threatened to expose names on her client list and was found hanging on her mother's property.

Designer Gianni Versace was gunned down in broad daylight on the steps of his Miami Beach mansion; those closest to Versace, and his killer Andrew Cunanan, try to unravel the mystery.

After American Atheists founder Madalyn Murray O'Hair disappears, the discovery of a mutilated body helps police catch the culprit.

Two people witness a truck driving over an unconscious man and flee into a nearby bar, but when the police turn up, the truck, the man and the witnesses are gone.

Insect evidence helps to solve the mystery of a woman found dead near a river bank.

A girl who is abducted and then released soon afterwards uses her knowledge of forensics to lead police to the kidnapper.

A trash collector finds a severed human leg in a trash bin but police cannot use conventional methods of victim identification; investigators turn to toxicology and DNA tests to find the murder-mutilator.

A coroner finds telltale clues on the badly burned body of a murder victim, sending police in pursuit of a couple of killers.

A man is arrested and convicted for a series of sexual assaults in Indiana; years later, forensic developments reveal new facts about the case.

The murder of a young Seattle couple puzzles investigators until the victims' dog, Chief, leads police to the killer.

A handsome young doctor's fiancee experiences severe illness after revealing that she is pregnant, and launches her own investigation to determine if the doctor is somehow responsible.

A seemingly model citizen turns out to be a serial killer.

An abandoned, still-running car leads investigators to a body with unusual marks and a DNA trail that lead to the killer.

Police find fragments of deleted computer files leading them to suspect a woman's suicide is really murder.

A suspicious neighbor gives police a break in a cold case.

A family suspects their teenage daughter's new friends were involved in her disappearance.

When a 62-year-old man opens a car restoration business and becomes seriously ill, his doctors cannot find the cause, but forensics can; identification of a highly toxic metal in the victim's blood leads to his poisoner.

When a 6-year-old disappears, her father becomes the prime suspect; he fails a polygraph test and even confesses, but 10 years later, the investigation gets turned on its head.

Investigators build a makeshift tent around a woman's body and use super glue fumes to lift the killer's palm print from the victim's skin.

The disappearance of a mail-order bride proves suspicious when detectives learn that two of the Texas husband's previous wives had died in mysterious circumstances.

A trash collector finds a severed human leg in a trash bin but police cannot use conventional methods of victim identification; investigators turn to toxicology and DNA tests to find the murder-mutilator.

A coroner finds telltale clues on the badly burned body of a murder victim, sending police in pursuit of a couple of killers.

A man is arrested and convicted for a series of sexual assaults in Indiana; years later, forensic developments reveal new facts about the case.

The murder of a young Seattle couple puzzles investigators until the victims' dog, Chief, leads police to the killer.

A handsome young doctor's fiancee experiences severe illness after revealing that she is pregnant, and launches her own investigation to determine if the doctor is somehow responsible.

A seemingly model citizen turns out to be a serial killer.

An abandoned, still-running car leads investigators to a body with unusual marks and a DNA trail that lead to the killer.

Police find fragments of deleted computer files leading them to suspect a woman's suicide is really murder.

A suspicious neighbor gives police a break in a cold case.

A family suspects their teenage daughter's new friends were involved in her disappearance.

When a 62-year-old man opens a car restoration business and becomes seriously ill, his doctors cannot find the cause, but forensics can; identification of a highly toxic metal in the victim's blood leads to his poisoner.

When a 6-year-old disappears, her father becomes the prime suspect; he fails a polygraph test and even confesses, but 10 years later, the investigation gets turned on its head.

Investigators build a makeshift tent around a woman's body and use super glue fumes to lift the killer's palm print from the victim's skin.

The disappearance of a mail-order bride proves suspicious when detectives learn that two of the Texas husband's previous wives had died in mysterious circumstances.

A 33-year-old West Virginia husband and father seemingly dies in an accidental house fire; a closer look at the scene reveals a more sinister case.

July Fourth weekend leads to tragedy for a California family; to catch a killer, detectives utilize an unorthodox technique - analyzing bug fragments - to help put a murderer behind bars.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

A family mourns the unexpected death of a beloved grandmother at Christmas, and while local police assure everyone that she was the victim of a tragic accident and that there is no foul play, some things about the scene don't add up.

When a true crime hobbyist connects a Utah Jane Doe to an Ohio missing persons case, detectives are hard-pressed to solve the decades-old murder.

A young Colorado mother suddenly vanishes on Thanksgiving, but when police trace her cell phone, it leads them to a surprising character with an even more surprising story.

Eight days after she disappeared on her way to a family ski trip, an 18-year-old woman's partially nude body is found floating in a river in Wyoming; years later, DNA technology uncovers dark secrets that led to her demise.

An upscale apparel store in Bethesda, Md., is the site of a gruesome scene when an employee is killed and her co-worker is battered and tied up, but surveillance video and blood evidence shed further light on the crime.

When the 20-year-old clerk of an Atlanta-area smoke shop is gunned down during a robbery, investigators have only descriptions of the killers and the make of their getaway car; investigators use a videotaped confession to smoke out the killers.

California police are baffled when an innocent man's DNA is found at the scene of a deadly home invasion, and authorities team with the man's defense attorney.

A young mother is found murdered in her home and there are two suspects with ample motive, but an unusual interview and security camera footage have investigators puzzled.

A jeweler's search through old sales records helps police find likely suspects in the murder of elderly couple Edward Kowalzck and Gertrude Thompson.

A garbage bag leads police to a child's killer.

An investigation into the disappearance of a young woman uncovers a tooth that helps police solve a crime without a body.

The sensitive nose of a forensic examiner sniffs out murder.

Discovering that an assault suspect is left-handed is crucial to a police investigation dating back 16 years.

Forensic scientists try to find a way to "lift" the serial number from a shotgun that's their only clue in a case.

Investigating the worst arson spree in U.S. history - a rash of more than 75 fires near Seattle.

Computers aid the police and FBI in solving a string of crimes.

Using an anonymous letter and geographical profiling, investigators close in on a serial rapist, and a cleverly obtained DNA sample confirms their suspicions.

When a young boy has serious respiratory problems and his father shows signs of early Alzheimer's disease, a chance encounter with a stranger kicks off an investigation into the cause.

Police in St. Petersburg, Fla., use cell phone mapping, wiretapping and a host of forensic evidence to find a surgeon's killer.

A woman wins her release after being imprisoned for allegedly killing her mother in a car fire.

Authorities are able to apprehend a kidnapper because he allowed his victim to write a will on a telltale pad of paper.

Experts debate whether an apparent heart attack victim died from natural causes or alleged poisoning by his girlfriend.

When a 12-year-old was found dead in her home, police were left clueless until a string of burglaries months later. A trail of stolen goods may help solve a murder.

When 15 year-old Marlene Miller was murdered, it would take 24 years and several retrials before forensic scientists discovered the evidence to bring her killer to justice.

Detectives use a forged signature to find a woman's abductor.

A woman is killed two days before she was scheduled to testify against a man accused of assaulting her and the prime suspect has an alibi.

Discovering that an assault suspect is left-handed is crucial to a police investigation dating back 16 years.

Forensic scientists try to find a way to "lift" the serial number from a shotgun that's their only clue in a case.

Investigating the worst arson spree in U.S. history - a rash of more than 75 fires near Seattle.

Computers aid the police and FBI in solving a string of crimes.

Using an anonymous letter and geographical profiling, investigators close in on a serial rapist, and a cleverly obtained DNA sample confirms their suspicions.

When a young boy has serious respiratory problems and his father shows signs of early Alzheimer's disease, a chance encounter with a stranger kicks off an investigation into the cause.

Police in St. Petersburg, Fla., use cell phone mapping, wiretapping and a host of forensic evidence to find a surgeon's killer.

A woman wins her release after being imprisoned for allegedly killing her mother in a car fire.

Authorities are able to apprehend a kidnapper because he allowed his victim to write a will on a telltale pad of paper.

Experts debate whether an apparent heart attack victim died from natural causes or alleged poisoning by his girlfriend.

When a 12-year-old was found dead in her home, police were left clueless until a string of burglaries months later. A trail of stolen goods may help solve a murder.

When 15 year-old Marlene Miller was murdered, it would take 24 years and several retrials before forensic scientists discovered the evidence to bring her killer to justice.

Detectives use a forged signature to find a woman's abductor.

A woman is killed two days before she was scheduled to testify against a man accused of assaulting her and the prime suspect has an alibi.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

One of the most prolific rapists and serial killers in Alaska's history; for more than a decade, The Butcher Baker kidnapped young women and brought them into the wilderness and hunted them like prey.

For years, The Butcher Baker serial killer was hiding in plain sight; he presented himself as a soft-spoken family man; one woman's story leads police to a shocking discovery inside Robert Hansen's home.

In November 1974, the DeFeo family were found murdered inside their beautiful seaside home; the mother, father and four of their children were shot in the back as they lay sleeping in their beds.

Para psychologists and psychics descend on the house to investigate who murdered the DeFeo family and why.

Revisiting an investigation into the case of an 8-year-old girl who was abducted, raped, and left for dead in 1968.

With a string of murders already behind him, Rodney Alcala appears on the TV show The Dating Game where he wins the prize: a date; ultimately Rodney is rejected by the girl, which many believe triggered yet another rampage of serial killings.

A bite mark is all the evidence needed to convict a suspect who was robbing tourists in Florida.

Technology able to analyze human bite-marks yields information on a woman's death.

A death in Pennsylvania is strikingly similar to one in North Carolina.

When a nurse starts experiencing a variety of flu-like symptoms, she discovers that she is HIV-positive; she learns that her infection was not accidental.

time of death becomes pivotal when a pregnant woman is found murdered in her air-conditioned bedroom.

An obscure print found at a crime scene.

A diner in a small town, an endocrinologist and a forensic botanist help destroy a prime suspect's alibi.

Neighbors do not hear the gunshots when a union official is killed in his home.

A man tells police he shot an intruder who murdered his wife; forensic evidence leads police to re-examine the man's motives.

A police officer claims his estranged wife's shooting death was a suicide, but investigators think it was a murder.

When fire fighters find a family dead inside their home, it appears to be a murder-suicide; clues at the scene lead investigators to believe otherwise.

A couple's murder leads investigators into the world of white supremacists and a string of hate crimes.

A rare gun and a victim's beloved dog help investigators trying to solve a multi-year long murder case where most of the witnesses were admitted drug users.

A search in Virginia's DNA databank reveals the identity of a news producer's murderer.

A homicide detective claims his wife accidentally shot herself in the head, but the evidence indicates otherwise.

Officials probe the death of a woman investigating the possible side effects of the drug she was prescribed for bipolar disorder.

A chip of stainless steel brings a killer to justice 20 years after a woman's body is found in a ravine.

An 11-year-old girl is sexually assaulted and shot twice at close range.

time of death becomes pivotal when a pregnant woman is found murdered in her air-conditioned bedroom.

An obscure print found at a crime scene.

A diner in a small town, an endocrinologist and a forensic botanist help destroy a prime suspect's alibi.

Neighbors do not hear the gunshots when a union official is killed in his home.

A man tells police he shot an intruder who murdered his wife; forensic evidence leads police to re-examine the man's motives.

A police officer claims his estranged wife's shooting death was a suicide, but investigators think it was a murder.

When fire fighters find a family dead inside their home, it appears to be a murder-suicide; clues at the scene lead investigators to believe otherwise.

A couple's murder leads investigators into the world of white supremacists and a string of hate crimes.

A rare gun and a victim's beloved dog help investigators trying to solve a multi-year long murder case where most of the witnesses were admitted drug users.

A search in Virginia's DNA databank reveals the identity of a news producer's murderer.

A homicide detective claims his wife accidentally shot herself in the head, but the evidence indicates otherwise.

Officials probe the death of a woman investigating the possible side effects of the drug she was prescribed for bipolar disorder.

A chip of stainless steel brings a killer to justice 20 years after a woman's body is found in a ravine.

An 11-year-old girl is sexually assaulted and shot twice at close range.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

Melanie Zanona; Catherine Lucey; Isaac Arnsdorf.

Newlywed Lauren Phelps is stabbed 123 times as she fights for her life; her killer may blame his deadly rampage on cold medicine.

After Florida mother Gretchen Anthony, 51, goes missing from her home, surveillance video tells a twisted tale of her final hours.

A romantic and scenic early morning boat ride turns deadly when Larry Isenberg falls overboard; investigators reveal the disappearance of half a million dollars, which could be motive for murder.

Twenty-four-year-old Alex Woodworth is brutally stabbed 16 times and left for dead hanging halfway out of the killer's car; as investigators peel back the layers, it's revealed the killer's many lovers is motive for murder.

Recently divorced mom-of-three Ingrid Lyne goes back into the dating scene and meets a man online, but her date at a baseball game will be her last; Seattle residents and investigators are shocked by a chilling crime scene.

A woman is killed weeks before testifying against the man who sexually assaulted her.

New York police hunt the Zodiac killer after a series of deadly attacks.

When a healthy young man dies mysteriously in his sleep, toxicology tests reveal that it may have been foul play. Could a `suicide note' hold the key to solving the case.

A child's memory, a diary and a forensic psychologist help investigators solve a young woman's murder.

Investigators weigh several theories while probing the death of a retired police officer, including a botched robbery and suicide.

The bodies of two young women are found in the ashes of an apartment fire.

Two different men report the murder of a single mother and when the case's other anomalies stall the police, a candy wrapper and seeds help expose the killer.

After a Connecticut man's body is found in a burning rental car on a Mexican highway, an insurance company suspects a scam.

When a pipe bomb rips through a rural home, killing a young man and seriously injuring his mother, detectives hope that the remnants of a mailing label will lead them to a killer.

A quiet residential community, shattered by the murder of a neighbor. See how modern techniques helped investigators catch the culprit in less than 12 hours.

A man is found dead in his Michigan auto-salvage shop.

A man is murdered in a drive-by shooting. When a mobile phone trace incriminates a killer, it's up to a forensic geologist to find evidence that he was at the scene.

When a teenage girl is found dead, her boyfriend confesses to her murder. However, in a strange twist, so does another man; police must determine which is the killer.

A high school gym teacher gives his friend a ride home but never returns; his wife and friend receive letters saying he started a new life, but they suspect foul play despite no body being discovered.

A 16-year-old girl is killed in her own home by her mother and father. Her parents said they acted in self-defense, but the forensic evidence indicates otherwise.

Investigators determine if a computer crash which almost ruined a manufacturing company was accidental or deliberate sabotage.

Car with three Secret Service agents collides with local deputy's car; investigation launched into who was responsible for the deadly car accident finds two very different conclusions.

The derailment of the Sunset Limited was the deadliest train crash in U.S. history killing 47 passengers and crew with several more injured.

Investigators weigh several theories while probing the death of a retired police officer, including a botched robbery and suicide.

The bodies of two young women are found in the ashes of an apartment fire.

Two different men report the murder of a single mother and when the case's other anomalies stall the police, a candy wrapper and seeds help expose the killer.

After a Connecticut man's body is found in a burning rental car on a Mexican highway, an insurance company suspects a scam.

When a pipe bomb rips through a rural home, killing a young man and seriously injuring his mother, detectives hope that the remnants of a mailing label will lead them to a killer.

A quiet residential community, shattered by the murder of a neighbor. See how modern techniques helped investigators catch the culprit in less than 12 hours.

A man is found dead in his Michigan auto-salvage shop.

A man is murdered in a drive-by shooting. When a mobile phone trace incriminates a killer, it's up to a forensic geologist to find evidence that he was at the scene.

When a teenage girl is found dead, her boyfriend confesses to her murder. However, in a strange twist, so does another man; police must determine which is the killer.

A high school gym teacher gives his friend a ride home but never returns; his wife and friend receive letters saying he started a new life, but they suspect foul play despite no body being discovered.

A 16-year-old girl is killed in her own home by her mother and father. Her parents said they acted in self-defense, but the forensic evidence indicates otherwise.

Investigators determine if a computer crash which almost ruined a manufacturing company was accidental or deliberate sabotage.

Car with three Secret Service agents collides with local deputy's car; investigation launched into who was responsible for the deadly car accident finds two very different conclusions.

The derailment of the Sunset Limited was the deadliest train crash in U.S. history killing 47 passengers and crew with several more injured.

A fire leads investigators to reexamine an unusual death.

A young woman's naked body is discovered in a remote area leading forensic investigators on a search for clues to her identity and the identity of her killer.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

He was a family-man, living in a New Jersey suburb with his wife and three kids but unbeknownst to his neighbors, Richard Kuklinski held a dark secret: he was the Iceman, a cold-blooded killer.

For many years, the Iceman, Richard Kuklinski, had literally gotten away with murder, but investigators were on to him; there was very little evidence, connecting the Iceman to his crimes.

A string of horrifying fires plagues California in the Eighties and Nineties, one of them fatally trapping four people inside.

In a race against time, investigators hunt for an arsonist setting devastating fires across California; to their complete shock, the man responsible turns out to be none other than renowned fire investigator Captain John Orr.

Arson investigators attempt to determine the cause of the 1987 fire at the Kings Cross Underground Station in London.

A discarded sleeping bag, containing bloody sneakers and a purse, leads police to the body of a young woman; a mark found on the victim's body enables police to track the killer.

A woman's apparent accidental death begins to look fishy after police uncover a letter written by the victim days before her untimely death.

An Alaskan trooper finds a woman's body beside a frozen road, but evidence is scant even after a suspected murder weapon is found.

Police link a clump of hair discovered in an isolated area with a woman who disappeared 20 years ago.

A news anchor is shot to death outside her home in an apparent crime of passion by a fan; a police dog tracks the scent of the killer back to the crime scene.

A fire, caused by an unattended cigarette, kills the estranged wife of a police officer; forensic scientists discover that the cause is far more complicated.

A trio of men, responsible for several bank robberies, leaves no evidence behind; forensic scientists help catch them by looking at the criminals' posture and clothing.

When a woman's bone marrow test reveals arsenic poisoning, investigators try to determine if it is due to groundwater contamination or something more sinister.

A missing bank president's body is found floating in a lake; the duct tape used in binding him to a chair helps solve the crime.

A husband was shot and killed, forensic psychiatry helped the wife to remember the details for what happened.

The body of a 16-year-old girl is discovered nine months after her disappearance; forensic scientists find clues that paint a virtual portrait of her killer.

A young woman falls to her death in what appears to be a tragic accident; a forensic exam of photos taken at the scene tells a different story.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

The robbery and brutal murder of an elderly couple goes unsolved for 10 years; a forensic scientist makes history when he solves the crime.

A man is charged with the murder of a wrestling champion; six years later, a forensic animator testifies on his behalf.

A 19-year-old girl is found dead in her car in what appears to be a suicide; police discover that the victime was involved in a love quadrangle, giving several people motive to kill.

Fifteen years after a man disappears, using a metal detector, police find evidence which proves what had happened.

Police link a clump of hair discovered in an isolated area with a woman who disappeared 20 years ago.

A news anchor is shot to death outside her home in an apparent crime of passion by a fan; a police dog tracks the scent of the killer back to the crime scene.

A fire, caused by an unattended cigarette, kills the estranged wife of a police officer; forensic scientists discover that the cause is far more complicated.

A trio of men, responsible for several bank robberies, leaves no evidence behind; forensic scientists help catch them by looking at the criminals' posture and clothing.

When a woman's bone marrow test reveals arsenic poisoning, investigators try to determine if it is due to groundwater contamination or something more sinister.

A missing bank president's body is found floating in a lake; the duct tape used in binding him to a chair helps solve the crime.

A husband was shot and killed, forensic psychiatry helped the wife to remember the details for what happened.

The body of a 16-year-old girl is discovered nine months after her disappearance; forensic scientists find clues that paint a virtual portrait of her killer.

A young woman falls to her death in what appears to be a tragic accident; a forensic exam of photos taken at the scene tells a different story.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

The robbery and brutal murder of an elderly couple goes unsolved for 10 years; a forensic scientist makes history when he solves the crime.

A man is charged with the murder of a wrestling champion; six years later, a forensic animator testifies on his behalf.

A 19-year-old girl is found dead in her car in what appears to be a suicide; police discover that the victime was involved in a love quadrangle, giving several people motive to kill.

Fifteen years after a man disappears, using a metal detector, police find evidence which proves what had happened.

When a Yale student mysteriously vanishes days before her wedding, investigators comb a secure research lab for clues.

A suitcase leads to the gruesome discovery of a nearly perfect crime.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

In 2008, two-year-old Florida toddler, Caylee Anthony, vanishes; her mother, Casey Anthony tells investigators Caylee has been kidnapped by her nanny, a woman Casey's family has never actually seen.

In 2008, two-year-old Florida toddler, Caylee Anthony, vanishes; her mother, Casey Anthony tells investigators Caylee has been kidnapped by her nanny, a woman Casey's family has never actually seen.

In the 1970s, hundreds of people began disappearing without a trace, but in 1997, shocking news about a mysterious religious group made headlines around the world and some answers finally came to light.

In May 2001 in Washington DC, 24-year-old intern Chandra Levy vanishes into thin air; police find her keys and her cell phone in her apartment and no sign of a struggle.

The body of a young California co-ed under an isolated interstate ramp sets off an investigation; San Diego police have no idea who would want her dead, but they discover a tiny, unique fiber on the victim's clothing.

Police become suspicious of a man who reported his wife missing 15 years after doing the same thing with his first wife.

While investigating the case of a Colorado hunter shot three times and killed, police suspect two murder weapons, and two killers, but forensic evidence points them closer to home.

A serial arsonist burns thousands of California homes and businesses.

A small community in upstate New York is devastated when a car accident claims the life of a well-respected nurse.

A woman disappears without a trace, and police learn two other women vanished under similar circumstances.

Hikers near Anchorage, Alaska discover a body wrapped in sheets edged in orange stitching; they discover threads of evidence clinging to the sheet.

The son of a murder victim contacts the police when a flight attendant is brutally murdered in a remarkably similar way.

A two-man shrimp boat sinks when a fast-moving, violent storm struck the Louisiana coast; a deckhand is considered a hero for trying to save the drowned captain, until his body is found.

A real estate tycoon must have had a premonition about foul play, as he wrote it in his will.

The cold-blooded murder of an American tourist in a Mexican resort causes law enforcement to focus on both sides of the border.

When a prominent banker's wife is kidnapped, the trail leads police on a wild goose chase; they track down disgruntled bank customers and examine computer fonts.

A man has no recollection of events after stabbing his wife and holding her head underwater in a swimming pool.

A fire investigator determines if a kerosene heater is the cause of a fire that killed one person or if it was murder.

California police in 1957 search for a murderer, but the case goes cold; 50 years after a crime is committed, advances in computer technology determine the killer.

Investigators piece together tiny clues at the scene of a hit-and-run accident; their findings help to track down the offending driver.

Investigators determine what caused a house fire that killed an elderly couple and whether the victims' son is responsible.

Detectives are suspicious after a woman is killed in a hunting accident, but it takes more than twenty years before a trace evidence analyst is able to match fibers on a soiled blanket to the killer.

A small community in upstate New York is devastated when a car accident claims the life of a well-respected nurse.

A woman disappears without a trace, and police learn two other women vanished under similar circumstances.

Hikers near Anchorage, Alaska discover a body wrapped in sheets edged in orange stitching; they discover threads of evidence clinging to the sheet.

The son of a murder victim contacts the police when a flight attendant is brutally murdered in a remarkably similar way.

A two-man shrimp boat sinks when a fast-moving, violent storm struck the Louisiana coast; a deckhand is considered a hero for trying to save the drowned captain, until his body is found.

A real estate tycoon must have had a premonition about foul play, as he wrote it in his will.

The cold-blooded murder of an American tourist in a Mexican resort causes law enforcement to focus on both sides of the border.

When a prominent banker's wife is kidnapped, the trail leads police on a wild goose chase; they track down disgruntled bank customers and examine computer fonts.

A man has no recollection of events after stabbing his wife and holding her head underwater in a swimming pool.

A fire investigator determines if a kerosene heater is the cause of a fire that killed one person or if it was murder.

California police in 1957 search for a murderer, but the case goes cold; 50 years after a crime is committed, advances in computer technology determine the killer.

Investigators piece together tiny clues at the scene of a hit-and-run accident; their findings help to track down the offending driver.

Investigators determine what caused a house fire that killed an elderly couple and whether the victims' son is responsible.

Detectives are suspicious after a woman is killed in a hunting accident, but it takes more than twenty years before a trace evidence analyst is able to match fibers on a soiled blanket to the killer.

A popular handyman in a New Hampshire town is found murdered and investigators follow forensic clues to a shocking conclusion.

A young mother is murdered in a crowded parking lot in broad daylight.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

19-year-old Sarah Stern vanishes just before Christmas and her car is found abandoned by Shark River; but the missing persons case soon turns into a homicide, and cops start focusing on a prom date.

Young mom of two, Kelley Stage, is found brutally murdered in her home after her husband returns from a night of poker; her young child witnesses the crime and reveals shocking details to investigators.

A young Colorado mom disappears on Thanksgiving Day and was last seen on grocery store surveillance with her baby; police soon uncover a brutal crime scene at her home and expose a twisted love triangle.

Tina Herrmann, her two children and a family friend disappear.

When hunters find a skull in a Texas canyon, police find bits of clothing, a woman's shoe, some small bones and a strand of hair; once they discover her identity, it was time to find the killer.

A wife is missing in Key West; investigators wonder if they should be searching for a missing person or a killer.

Suicide notes and a pistol in hand lead police to suspect that a mother of two young children appeared to had killed herself, but when investigators learned of a house fire she was in three years earlier, they reinvestigate.

The violent death of an Air Force officer's wife outside a Philippines air base is examined, amid accusations of a love triangle involving the murdered woman's husband; investigators use groundbreaking computer forensics to make their case.

Pieces of plastic the size of sand hold clues to a bombing.

At first glance it appears a young woman suffocated, but further investigation shows the scene was staged.

A killer is careless when a home is destroyed by fire and a young boy is missing.

A patrol officer is shocked by the amount of blood at a traffic accident and is shocked by the coroner's ruling until an anonymous phone call re-ignites the case.

An irrigation canal murder remains unsolved until a similar murder occurs.

The light of day and DNA picture painted by molecular biologist reveals new clues about a nighttime traffic accident.

On Valentine's Day, an obstetrician finds his wife dead and calls 911; police discover inconsistencies between the blood spatter evidence and his version of events.

Weed analysis and photogrammetry are used to help solve the 1995 murder of a California teenager is found dead after disappearing from her home.

When police recover the submerged car of missing man, they find no body; the investigation that follows uncovers a deadly obsession and the motive for murder.

Emergency dispatch recieved a call from a man who said his girlfriend shot and killed herself. But the wound was not self-inflicted.

Investigators piece together evidence found at the scene of a Native American woman's murder; the tyre tracks and shoe impressions could lead them to the killer.

Experts seek answers to a young businesswoman's death just before she was to testify in a criminal trial.

An anonymous caller reports the rape and murder of a dry cleaner employee; two eyewitnesses tell two similar but not identical stories.

Police blame a botched robbery when an eccentric elderly millionaire is found dead, but the motive could be wrong.

Pieces of plastic the size of sand hold clues to a bombing.

At first glance it appears a young woman suffocated, but further investigation shows the scene was staged.

A killer is careless when a home is destroyed by fire and a young boy is missing.

A patrol officer is shocked by the amount of blood at a traffic accident and is shocked by the coroner's ruling until an anonymous phone call re-ignites the case.

An irrigation canal murder remains unsolved until a similar murder occurs.

The light of day and DNA picture painted by molecular biologist reveals new clues about a nighttime traffic accident.

On Valentine's Day, an obstetrician finds his wife dead and calls 911; police discover inconsistencies between the blood spatter evidence and his version of events.

Weed analysis and photogrammetry are used to help solve the 1995 murder of a California teenager is found dead after disappearing from her home.

When police recover the submerged car of missing man, they find no body; the investigation that follows uncovers a deadly obsession and the motive for murder.

Emergency dispatch recieved a call from a man who said his girlfriend shot and killed herself. But the wound was not self-inflicted.

Investigators piece together evidence found at the scene of a Native American woman's murder; the tyre tracks and shoe impressions could lead them to the killer.

Experts seek answers to a young businesswoman's death just before she was to testify in a criminal trial.

An anonymous caller reports the rape and murder of a dry cleaner employee; two eyewitnesses tell two similar but not identical stories.

Police blame a botched robbery when an eccentric elderly millionaire is found dead, but the motive could be wrong.

A serial killer terrorizes a small Texas town.

A mysterious murder in an upscale community is solved by cell phone forensics.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

An eight-month-old baby is fatally injured while in the care of his nanny, Louise Woodward.

George Michael's life as international super star comes to a mysterious and tragic end on Christmas Eve 2016; family and fans were shocked by his sudden death.

It was the shocking affair that nearly toppled a Presidency - Bill Clinton and 21-year-old White House intern Monica Lewinsky.

It was the shocking affair that nearly toppled a presidency; Bill Clinton and a 21-year-old White House intern, Monica Lewinsky.

Woman disappears from grocery store parking lot in Boulder, Colo.; investigators find extraordinary clues in a pair of bloody gloves, unique tire tracks, and ordinary grass and pine needles.

Retracing the steps of real investigations with interviews and dramatic re-creations as experts draw on forensic science to solve baffling crimes and other mysteries.

Police suspect a gay college student's slaying is a hate crime until forensic evidence points the case in another direction.

In a wealthy area of Philadelphia, police are called to the scene of what seems like a regular accidental drowning; the investigation begins to focus on one person who has many reasons to want the victim dead.

Two women are murdered in the same town and police fear a serial killer is on the loose, further investigation finds that they were both close to the same man.

A young woman is found dead on a golf course in the Bahamas; the grass on that course is so distinctive that it had evidentiary value; the evidence leds police to two suspects; each blamed the other, and they have to find out who the killer is.

A teenager goes missing after an evening of horseback riding; her body is found a month later, three miles from her home; the killer unknowingly leaves a trace of evidence behind, tiny but unmistakable clues that pointed to him and him alone.

When a popular disc jockey is found murdered in a community garden, police swing into action; a sniffer dog and a blood spatter expert led police to the killer and he'd been much closer than they realize.

Investigators unravel a twisted tale of lust, greed and deception after a woman claims her husband was gunned down by intruders.

Three seemingly unrelated deaths proved to be serial murders; the killer had been careful, he uses poison which had no taste or odour, fortunately for investigators, it also has a unique chemical signature.

A man is murdered in his sleep but no fingerprints are anywhere to be found; a shoe impression outside could lead to the killer.

With very little else to go on, investigators find that a show impression puts them on the right track to finding a killer in Lansing, Mich.

The owner of a restaurant is killed; investigators uncover tales of debt and deceit, but the case remains open, until one detective gets inspired by an earlier episode of "Forensic Files," and looks for clues in an empty holster.

A serial arsonist was on the loose in Washington, DC. Each of the fires was started with the same type of incendiary device. The perpetrator was very careful, and seemed to leave no evidence behind... but there were clues in the ashes and it was up to forensic scientists to find them.

A man becomes the prime suspect in his wife's death after forensic science raises questions about her apparent suicide.

Investigators on both sides of the Atlantic seek links between three homicides that look like professional executions.

Who put a bomb in the home of a 29-year-old woman and killed her?

A killer tried to destroy everything which could link them to the crime; but in doing so, they inadvertently created new forensic evidence, evidence which came to light using a technique never before used in a criminal investigation.

Two women are murdered in the same town and police fear a serial killer is on the loose, further investigation finds that they were both close to the same man.

A young woman is found dead on a golf course in the Bahamas; the grass on that course is so distinctive that it had evidentiary value; the evidence leds police to two suspects; each blamed the other, and they have to find out who the killer is.

A teenager goes missing after an evening of horseback riding; her body is found a month later, three miles from her home; the killer unknowingly leaves a trace of evidence behind, tiny but unmistakable clues that pointed to him and him alone.

When a popular disc jockey is found murdered in a community garden, police swing into action; a sniffer dog and a blood spatter expert led police to the killer and he'd been much closer than they realize.

Investigators unravel a twisted tale of lust, greed and deception after a woman claims her husband was gunned down by intruders.

Three seemingly unrelated deaths proved to be serial murders; the killer had been careful, he uses poison which had no taste or odour, fortunately for investigators, it also has a unique chemical signature.

A man is murdered in his sleep but no fingerprints are anywhere to be found; a shoe impression outside could lead to the killer.

With very little else to go on, investigators find that a show impression puts them on the right track to finding a killer in Lansing, Mich.

The owner of a restaurant is killed; investigators uncover tales of debt and deceit, but the case remains open, until one detective gets inspired by an earlier episode of "Forensic Files," and looks for clues in an empty holster.

A serial arsonist was on the loose in Washington, DC. Each of the fires was started with the same type of incendiary device. The perpetrator was very careful, and seemed to leave no evidence behind... but there were clues in the ashes and it was up to forensic scientists to find them.

A man becomes the prime suspect in his wife's death after forensic science raises questions about her apparent suicide.

Investigators on both sides of the Atlantic seek links between three homicides that look like professional executions.

Who put a bomb in the home of a 29-year-old woman and killed her?

A killer tried to destroy everything which could link them to the crime; but in doing so, they inadvertently created new forensic evidence, evidence which came to light using a technique never before used in a criminal investigation.

After the brutal slaying of a young couple on a road trip, the victims' families begin receiving disturbing letters.

After a young mother is found brutally murdered in her home, investigators find startling clues on her cell phone that could lead to her killer.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

An amazing new forensic tool turns a cold case around.

A gruesome find in a small town church sends investigators searching for a killer.

An insurance agent is shot execution style in his office, but the killer leaves no fingerprints, and there are no murder weapon found at the scene; then investigators discover a critical clue invisible to the naked eye that cracks the case.

A healthy, young mother mysteriously dies after a minor traffic accident triggering an investigation.

Investigators search for clues after a body is discovered in a watery grave.

The murder of teacher's aide leaves a hole in the heart of her small community; as rumors spread about suspects, the actual perpetrator slips further away.

Father and teacher are found hanging naked from a tree with the letters F-E-D on his chest; with barely any evidence to work with, investigators turn to these letters for answers.

A single mom vanishes without a trace; foul play is confirmed after a truck toolbox opens with her body inside; homicide detectives investigate men she matched on dating sites, men from work, and a lover with a violent past.

After a tycoon's wife is found dead in her SUV submerged in a half-frozen creek, police begin to suspect it wasn't an accident.

A Russian immigrant is found dead and a strange phone call to his office is the only lead investigators have.

Physical evidence intially condemns a prime suspect to a double homicide, but DNA from a discarded spoon points to another.

A child's death from flu-like symptoms triggers an investigation that ranges from the United States to Egypt and uncovers murder.

A couple is found dead in a car with broken windows but no shattered glass.

Key suspect has a solid alibi in the murder of a war veteran; but police get a lead by finding a new suspect with a sweet tooth.

A woman who appeared to have taken her own life told her sister that, if anything were to happen to her, there was a note in the china cabinet.

When an aspiring model turns up dead, police suspect her boyfriend. But must dig deeper for clues when he is cleared.

Tiny fibers and an asthma inhaler are the clues that lead officers to the killer of an off-duty policeman.

Investigators search the world of high rollers and offshore betting to solve the first triple homicide in Verona, Wisc.

Police search every apartment building in town when the body of a young girl found on an isolated farm holds a set of keys but no ID.

A man denies killing a pedestrian in hit-and-run, claiming he sold the car in question, and authorities track down the car to find critical evidence.

Three years later, a second autopsy determines who's right when a medical examiner and detectives disagree on the cause of death.

Hit-and-run boating accident that kills a popular young man causes investigators to search for one boat out of thousands.

A woman is found dead on her bedroom floor, the only clue is a bloodstained sheet; breakthrough forensics enable police to identify the killer.

A young man was killed in a mysterious car crash, but the evidence at the scene led investigators to believe it was not an accident; forensic science revealed what really happened, and the truth devastated three families.

A woman is found dead, police use blood evidence and computer forensics to convince a jury that the murderer is guilty.

When an elderly woman dies in an apparent robbery-homicide, evidence suggests the suspect broke out of the house rather than breaking in.

A couple is found dead in a car with broken windows but no shattered glass.

Key suspect has a solid alibi in the murder of a war veteran; but police get a lead by finding a new suspect with a sweet tooth.

A woman who appeared to have taken her own life told her sister that, if anything were to happen to her, there was a note in the china cabinet.

When an aspiring model turns up dead, police suspect her boyfriend. But must dig deeper for clues when he is cleared.

Tiny fibers and an asthma inhaler are the clues that lead officers to the killer of an off-duty policeman.

Investigators search the world of high rollers and offshore betting to solve the first triple homicide in Verona, Wisc.

Police search every apartment building in town when the body of a young girl found on an isolated farm holds a set of keys but no ID.

A man denies killing a pedestrian in hit-and-run, claiming he sold the car in question, and authorities track down the car to find critical evidence.

Three years later, a second autopsy determines who's right when a medical examiner and detectives disagree on the cause of death.

Hit-and-run boating accident that kills a popular young man causes investigators to search for one boat out of thousands.

A woman is found dead on her bedroom floor, the only clue is a bloodstained sheet; breakthrough forensics enable police to identify the killer.

A young man was killed in a mysterious car crash, but the evidence at the scene led investigators to believe it was not an accident; forensic science revealed what really happened, and the truth devastated three families.

A woman is found dead, police use blood evidence and computer forensics to convince a jury that the murderer is guilty.

When an elderly woman dies in an apparent robbery-homicide, evidence suggests the suspect broke out of the house rather than breaking in.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

From 1987 to 1992, rapes, abductions and murders of young women occur north of the U.S.-Canadian border; a tip leads cops to an unlikely suspect: a blond, blue-eyed accountant who lives with his wife in a pink house in the suburbs.

From 1987 to 1992, rapes, abductions and murders of young women occur north of the U.S.-Canadian border; a tip leads cops to an unlikely suspect: a blond, blue-eyed accountant who lives with his wife in a pink house in the suburbs.

When college-aged women in Charlottesville, Va. go missing, the search for answers leads authorities to local star athlete Jesse Matthew Jr.; in a shocking story, two women are killed, but another survives to bring the murderer to justice.

When college-aged women in Charlottesville, Va. go missing, the search for answers leads authorities to local star athlete Jesse Matthew Jr.; in a shocking story, two women are killed, but another survives to bring the murderer to justice.

Sammy the Bull Gravano was the right-hand man to mafia kingpin, John Gotti and carried out multiple murders; after his arrest, he breaks the sacred oath of silence and cuts a deal with the government, testifying against his former boss.

Sammy the Bull Gravano was the right-hand man to mafia kingpin, John Gotti and carried out multiple murders; after his arrest, he breaks the sacred oath of silence and cuts a deal with the government, testifying against his former boss.

Wealthy man is shot dead while his wife is forced to open their hidden safe, but they couldn't be identified because they were wearing ski masks.

The bomb was constructed to cause as much damage as possible and it did, killing the victim with deadly force and flame; a painstaking search yielded tiny clues, which identified the killer as surely as if he'd signed them.

A twelve-year-old girl claims that she was abducted and sexually assaulted. However, her story seems unbelievable until police discover fibers on her clothing.

Police are suspicious of numerous bloodstains when a woman has a fatal fall down the stairs.

A decade old case reopens, and a few seconds of a 911 call enable investigators to determine who is responsible for a murder.

A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

A clue no bigger than a thumbtack leads investigators to a trio of killers.

For ten years, the disappearance of a college co-ed remained a mystery; new scientific testing cast a different light on a man who had been a suspect all along.

Tipster is found dead after revealing that a woman's death 16 years ago was murder.

The murder of 53-year-old Paul Gruber is examined and the evidence points to Darryl Robin Kuehl, who was later convicted of the crime.

Forensic science is used to determine if a woman's death was a botched robbery or intentional murder.

Detectives discover new clues left by a stalker's letter to his victim.